Tag: "metastases"

A Randomized Phase III Study Comparing Adjuvant 5-fluorouracil/Folinic Acid with FOLFIRI in Patients Following Complete Resection of Liver Metastases from Colorectal Cancer

A Randomized Phase III Study Comparing Adjuvant 5-fluorouracil/Folinic Acid with FOLFIRI in Patients Following Complete Resection of Liver Metastases from Colorectal Cancer

Abstract Background: Studies indicate that adjuvant 5-fluorouracil (5-FU) with folinic acid (FA) in colorectal cancer patients with completely resectable liver-limited metastases (LMCRC) offers clinical benefit over surgery alone. This phase III trial compared FOLFIRI with simplified 5-FU/FA in this setting. Patients and methods: LMCRC patients were randomized to receive every 14 days, FA, 400 mg/m2 [...]

Feb 12, 2010 | 0 comments | View Post
Radioembolization With Systemic Therapy

Radioembolization With Systemic Therapy

The majority of patients with advanced colorectal cancer die from hepatic metastases caused by disease progression; therefore, several novel technologies are in clinical development to potentially improve local control of liver disease. Radioembolization is a technique for administering radiotherapy internally to unresectable primary or secondary hepatic malignancies in a single procedure. This technique involves the [...]

Jan 06, 2010 | 1 comment | View Post