The Rituximab significantly lowers level of glycated hemoglobin and required less insulin
Researcher believed that only T-lymphocyte autoimmunity is the major role in immunopathogenesis of type 1 diabetes mellitus, but nowadays growing evidence conclude that B lymphocyte also play a crucial role in many T-lymphocyte Mediated diseases, for this researcher developed the drug rituxmab ,an anti-CD 20 monoclonal ,which depleted CD19+ B lymphocytes. The Rituximab significantly lowers level of glycated hemoglobin and required less insulin.
Reference:
New england journal of Medicine ,Volume 361:2143-2152 November 26,2009
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Most people get Diabetes because of the lack of exercise and overeating. We should be more aware of our lazy lifestyles and start exercising regulary to avoid Type II Diabetes.