Comments on: what is this case??? http://www.drknp.com/medicine/endocrine/what-is-this-case Complete source of medicine Wed, 04 Jan 2012 14:30:57 +0000 hourly 1 http://wordpress.org/?v=3.3.1 By: ukesh http://www.drknp.com/medicine/endocrine/what-is-this-case/comment-page-1#comment-125 ukesh Thu, 31 Dec 2009 09:50:35 +0000 http://www.drknp.com/?p=326#comment-125 I think this is the case of Primary hyperaldosteronism,either it is due to 1)unilateral aldosterone-producing adenoma (APA) or Conn syndrome (50-60% of cases) and (2) idiopathic hyperaldosteronism (IHA) or bilateral adrenal hyperplasia (40-50% of cases).Because imaginary diagnostic major was not mention,the actual cause of primary hyperaldesteronism either by APA or by IHA can't be differntiated.Increase in aldosterone increase renal distal tubular reabsorption of sodium, enhances secretion of potassium and hydrogen ions, causing hypernatremia, hypokalemia, and alkalosis.And alkalosis causes increase binding of free calcium with albumin results in hypocalcemia. I think this is the case of Primary hyperaldosteronism,either it is due to 1)unilateral aldosterone-producing adenoma (APA) or Conn syndrome (50-60% of cases) and (2) idiopathic hyperaldosteronism (IHA) or bilateral adrenal hyperplasia (40-50% of cases).Because imaginary diagnostic major was not mention,the actual cause of primary hyperaldesteronism either by APA or by IHA can’t be differntiated.Increase in aldosterone increase renal distal tubular reabsorption of sodium, enhances secretion of potassium and hydrogen ions, causing hypernatremia, hypokalemia, and alkalosis.And alkalosis causes increase binding of free calcium with albumin results in hypocalcemia.

]]> By: admin http://www.drknp.com/medicine/endocrine/what-is-this-case/comment-page-1#comment-123 admin Wed, 30 Dec 2009 15:19:33 +0000 http://www.drknp.com/?p=326#comment-123 this is the case of conn,s disease.....in which aldosterone is increases that acts on distal convoluted tubules to reabsorption of sodium at the expense of potassium. During Na++ reabsorption water is also absorbed that leads to hypertension ......and the rest of the symptoms is due to lower serum potassium level....... this is the case of conn,s disease…..in which aldosterone is increases that acts on distal convoluted tubules to reabsorption of sodium at the expense of potassium. During Na++ reabsorption water is also absorbed that leads to hypertension ……and the rest of the symptoms is due to lower serum potassium level…….

]]> By: Zenith http://www.drknp.com/medicine/endocrine/what-is-this-case/comment-page-1#comment-121 Zenith Wed, 30 Dec 2009 10:35:21 +0000 http://www.drknp.com/?p=326#comment-121 Hypokalemic paralysis due to primary hyperaldosteronism simulating gitelman's syndrome. Also, Conn's syndrome and Gitel­man's syndrome should be considered in a differential diagnosis of patients with hypokalemic paralysis due to occasional overlapping laboratory findings. Hypokalemic paralysis due to primary hyperaldosteronism simulating gitelman’s syndrome.

Also, Conn’s syndrome and Gitel­man’s syndrome should be considered in a differential diagnosis of patients with hypokalemic paralysis due to occasional overlapping laboratory findings.

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