Category: Endocrine

Felty’s syndrome

Felty’s syndrome

Felty’s syndrome is potentially serious condition characterized by triad of rheumatoid arthritis, splenomegaly and abnormally low white blood count.

Antiphospholipid syndrome

Antiphospholipid syndrome

Antiphospholipid syndrome is a condition characterized by blood clots (thrombosis) in both arteries and veins and various other problems, some life-threatening.

Barraquer–Simons syndrome

Barraquer–Simons syndrome

Barraquer-Simons syndrome is a rare childhood diseases characterized by the gradual onset of bilaterally symmetrical loss of subcutaneous fat from the face

Recombinant Human Growth Hormone and GH Deficiency

Recombinant Human Growth Hormone and GH Deficiency

Growth hormone (GH) is species-specific, and humans do not respond to GH derived from animals. In the past, the only human GH available for treating children who were GH-deficient

Pancreatic Beta cell Function and c- peptide

Pancreatic Beta cell Function and c- peptide

Beta cells of the human pancreas produce and secrete insulin. The product of the insulin gene is a peptide known as Preproinsulin. As with other secretory peptides, the prepeptide or signal peptide is cleaved off early in the biosynthetic process, yielding proinsulin. Proinsulin is an 86-amino acid protein that is subsequently cleaved at two sites to [...]

Autoimmune Thyroid Disease-Postpartum Thyroiditis

Autoimmune Thyroid Disease-Postpartum Thyroiditis

Certain disease affecting the function of the thyroid gland occur when and individuals immune system fails to recognize particular thyroid proteins as ‘self’ and

The diabetes foot

The diabetes foot

Despite efforts to control their disease and maintain a normal glycemic state, most persons with diabetes eventually develop one or more secondary

Metabolic acidosis in Diabetes Mellitus

Metabolic acidosis in Diabetes Mellitus

Diabetes mellitus is a common disorder characterized by an insufficient secretion of insulin resistance by the major target tissue (skeletal muscle, liver, and adipocytes). A severe metabolic

A case report

A case report

Hepatic involvement in Wegener’s granulomatosis: a case report Journal of Medical Case Reports 2010, 4:9 doi:10.1186/1752-1947-4-9 Constantin Goritsas (cpgor@otenet.gr) Nicolas P Paissios (paissios@gmail.com) Rodoula Trigidou (trigidou@otenet.gr) Joanna Delladetsima (jokadelladetsima@hotmail.com Abstract Introduction Report the case of a 58-year-old Caucasian Greek man who presented with dry cough, fever, bilateral alveolar infiltrates and acute hepatitis. Case presentation After [...]

what is this case???

what is this case???

A 30 year-year-old woman was admitted to the emergency department with a sudden onset of progressive paralysis involving four extremities. She denied having nausea, vomiting, diarrhea or the use of drugs, including diuretics and licorice. Her family history was un remarkable. One year ago she had presented to the hospital with muscle weakness and myalgias. [...]

Why there is elevated AST and ALD in grave's disease??

Why there is elevated AST and ALD in grave’s disease??

Why there is elevated AST and ALD in grave’s disease?? plz explain the reason …..

do you know?

in treanment of hypopituitarism, we have to give the corticosteroids, thyroid hormones,sex hormones replacement(if they are deficit).   initially we should give corticosteroid or we can give corticosteroid and thyroid  hormone at a same time but NEVER  give thyroid hormone first.  why? do you have any idea?

why there is hypocalcemia in severe pancreatitis?

According to the modified glasgow criteria for pedicting severity of pancreatitis ,(mnemonic as PANCREAS).Do you  know guys,, why there  is low  serum calcium in patients with severe pancreatitis?? recently i have gone through harrison’s and it is written that, the pathogenesis  is still unknown.it is said that one reason maybe due to intraperitoneal saponification of calcium by fatty [...]