Author Archive for drprakash

HAPPY HOLI TO U ALL

HAPPY HOLI TO U ALL

Holi, also called the Festival of Colours, is a spring festival celebrated by Hindus, Buddhist

Asperger syndrome

Asperger syndrome

Asperger syndrome also called as Asperger disorder or Asperger’s in an autism spectrum (Characterized by widespread abnormalities of social interactions and communication,

A Randomized Phase III Study Comparing Adjuvant 5-fluorouracil/Folinic Acid with FOLFIRI in Patients Following Complete Resection of Liver Metastases from Colorectal Cancer

A Randomized Phase III Study Comparing Adjuvant 5-fluorouracil/Folinic Acid with FOLFIRI in Patients Following Complete Resection of Liver Metastases from Colorectal Cancer

Abstract Background: Studies indicate that adjuvant 5-fluorouracil (5-FU) with folinic acid (FA) in colorectal cancer patients with completely resectable liver-limited metastases (LMCRC) offers clinical benefit over surgery alone. This phase III trial compared FOLFIRI with simplified 5-FU/FA in this setting. Patients and methods: LMCRC patients were randomized to receive every 14 days, FA, 400 mg/m2 [...]

Advances in the Diagnosis and Treatment of Small Bowel Lesions with Crohn’s Disease using Double-balloon Endoscopy

Advances in the Diagnosis and Treatment of Small Bowel Lesions with Crohn’s Disease using Double-balloon Endoscopy

Crohn’s disease was first reported by Crohn et al. in 1932 as ‘regional ileitis’ with chronic granulomatous inflammation of the terminal ileum [Chron et al. 2000].

In the Neo-adjuvant Treatment of Gastro-esophageal Cancers

In the Neo-adjuvant Treatment of Gastro-esophageal Cancers

Pre- and peri-operative strategies are becoming standard for the management of Localized gastro-esophageal cancer. For localized gastric/gastro-esophageal junction (GEJ) cancer there are conflicting data that a peri-operative approach with cisplatin-based chemotherapy improves survival, with the benefits seen in esophageal cancer likely less than a 5—10% incremental improvement. Further trends toward improvement in local control and [...]

Painless macroscopic hematuria

Painless macroscopic hematuria

A 60-year-old woman is referred to the emergency department (ED) because of a recent event of painless macroscopic hematuria. She reports having experienced several similar episodes during the past year, all of which resolved spontaneously. She regards these episodes as being of gynecologic origin because she is 5 years postmenopausal. She describes a general feeling [...]

Early Physiotherapy May Help Prevent Lymphedema After Breast Cancer Surgery

Early Physiotherapy May Help Prevent Lymphedema After Breast Cancer Surgery

“”Efforts have been made to reduce the risk of secondary lymphoedema by preoperative and postoperative counselling and education and by early detection.” The goal of this study was to assess the efficacy of early physiotherapy in reducing the risk for secondary lymphedema after surgery for breast cancer. At a university hospital in Madrid, Spain, 120 [...]

Guideline on Surgical Management of Stress Urinary Incontinence

Guideline on Surgical Management of Stress Urinary Incontinence

“This Guideline advises physicians to counsel their patients and set expectations prior to undergoing treatment,” AUA Guideline Panel Chair Roger Dmochowski, MD, said in a news release. “This is very important because often the patient thinks that surgery will completely cure their incontinence, when in reality, it may only make modest improvements.” The new recommendations [...]

Recurrent Abdominal Pain .

Recurrent Abdominal Pain .

A 51-year-old woman presents to an outpatient surgical consultation for abdominal pain. She first noted the pain 9 months ago. She states that the pain occurs about every 3-4 weeks, and that each episode lasts 2-3 days at a time. The pain is described as “excruciating” when it occurs, causing her to double over, and [...]

A 77-Year-Old Man With Suddenly Worsened Abdominal Pain

A 77-Year-Old Man With Suddenly Worsened Abdominal Pain

A 77-year-old man presents to the emergency department (ED) in the early morning with a 4-hour history of severe, generalized abdominal pain. He describes some “cramp-like” abdominal pain and bilious vomiting yesterday, but states he simply “got on with things”. His condition had worsened considerably by late evening. He describes the sudden onset of generalized, [...]

QUIZ

A 3-year-old child presents with a petechial rash but is otherwise well and without physical findings. Platelet count is 20,000/μL; hemoglobin and WBC count are normal. Which of the following is the most appropriate therapy for this patient’s likely diagnosis? A. High-dose aspirin B.Therapeutic doses of iron C.Intravenous immunoglobulins D.Bone marrow transplant E.L-asparaginase which one is [...]

Radioembolization With Systemic Therapy

Radioembolization With Systemic Therapy

The majority of patients with advanced colorectal cancer die from hepatic metastases caused by disease progression; therefore, several novel technologies are in clinical development to potentially improve local control of liver disease. Radioembolization is a technique for administering radiotherapy internally to unresectable primary or secondary hepatic malignancies in a single procedure. This technique involves the [...]